The AUC of the active metabolite, N-desmethyl sildenafil, was elevated 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. These effects over the metabolite usually are not predicted to be of clinical consequence.
Hvis du er allergisk for noen av de aktive ingrediensene Når du tar potensstyrkende piller, skal du sørge for at du ikke tar medisiner som du ikke har nevnt i din on the net konsultasjon eller nevnt til din lege. Det er viktig å nevne både kosttilskudd, reseptfrie og reseptbelagte medisiner til legen for å utelukke uheldige interaksjoner.
VIAGRA does not safeguard you or your husband or wife from obtaining sexually transmitted disorders, together with HIV—the virus that causes AIDS.
Long-lasting harm to the penis could take place if priapism is not really dealt with immediately. End taking sildenafil and get emergency help Should you have any of the following indications of priapism.
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Alprostadil Injiserbar behandling som virker fra fem minutter. Godt alternativ hvis tabletter ikke har fungert.
At 24 hrs the plasma amounts of sildenafil ended up nevertheless roughly two hundred ng/mL, compared to somewhere around 5 ng/mL when sildenafil was dosed by yourself. This can be in line with ritonavir's marked outcomes with a wide array of P450 substrates. VIAGRA had no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].
The mean profiles of the change from baseline in standing systolic blood pressure in topics addressed with doxazosin together with 50 mg VIAGRA or matching placebo are revealed in Determine three.
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nett (ninety nine+) apotek Dette produktet hentes i apotek ved bestilling på nett Legg til som favoritt
More robust CYP3A4 inhibitors for example ketoconazole or itraconazole might be predicted to obtain better outcomes than found with saquinavir. A starting up dose of 25 mg of VIAGRA really should be regarded as in individuals getting erythromycin or strong CYP3A4 inhibitors (including saquinavir, ketoconazole, itraconazole) [see DOSAGE click here AND ADMINISTRATION, CLINICAL PHARMACOLOGY].
Dette kan spesielt være dersom tabletten tas med et stort eller fett måltid kan absorberingen av virkemiddelet forsinkes. Alkohol kan redusere effekten av potenspillen, og det anbefales derfor ikke at person tar medisinen i kombinasjon med overdrevne mengder alkohol.
Although the interaction among other protease inhibitors and sildenafil has not been researched, their concomitant use is anticipated to raise sildenafil ranges.
In situations of overdose, standard supportive steps really should be adopted as essential. Renal dialysis just isn't expected to speed up clearance as sildenafil is highly certain to plasma proteins and It's not removed within the urine.